Diosmin versus tranexamic acid in heavy menstrual bleeding: a randomized controlled trial

Background: Heavy menstrual bleeding (HMB) is defined as cyclical at regular intervals but excessive in amount which affect the physical, social and mental aspects of life a woman. The prevalence 10-30% reproductive age women 50% perimenopausal women. HMB not just clinical burden also huge economic burden. aims objective my study to compare efficacy diosmin tranexamic acid acute terms average duration cycle, PBAC/PABC score, endometrial thickness, hemoglobin concentration finally need for other modes treatment.Methods: was randomized control trial patients (sample size-72) were divided into two groups- group D (n=36) T (n=36). Group treated with tab 500 mg thrice daily from day 1 5 cycle. Similarly PBAC score taken end three months along thickness concentration. results compared values obtained before initiating treatment.Results: In this after 3 treatment; had an initial 423.52 treatment it decreased 149.89 (p<0.0001). Reduction 60.5%. 441which reduced 177.94 (p<0.0001) treatment. reduction 59.6%.Conclusions: found that both effective HMB, cycle thickness. But similar groups. failure rates groups, improvements only marginal